Tikhomirov’s primary works are considered groundbreaking in the activity theory community. In particular, his efforts in understanding the positive effects of computers on the development of creative activity provide valuable instruction to activity theorists, especially with respect to their influence on new goal formation. Tikhomirov’s quests to better understand “how computers affect the development of intellectual activity” are explicitly revealed in the clinical environment. As the intensive care unit is a preeminent environment to observe creative activity in real time, the primary problems of clinical team communication and collaboration, both aspects being related to joint activity, are identified. As one way to approach such a problem, Tikhomirov’s theory on creative activity is explained in the context of information technology. Then, distributed cognition theory and creative activity theory are joined together and extended into distributed-creative activity theory, as an augmentation of complex interpersonal cognition through the use of health information technology.