Women constitute a significant portion of the total business travel market in the U.S. This study aimed to explore travel risk and safety issues among women in higher education who regularly travel for work. Three focus groups were conducted with female faculty and staff at a major public university in the U.S. Results of an inductive-deductive analysis indicated three major themes, namely, risk perception, risk treatment, and risk adoption. Findings provide insights into how female higher education employees perceive risk and safety during business trips, and their travel behaviour that include actions taken to mitigate the potential risks or time-to-time risky decisions about travel arrangements. Further, recommendations are made for enhancement of travel policies at the institutional level to ensure safety of female employees.